Rajeshwar Reddy Kasarla

Department of Microbiology, Universal College of Medical Sciences, Bhairahawa, Nepal

https://orcid.org/0000-0001-5422-2328

Rahul Reddy Kasarla

Department of Orthopaedics, Medivison Super Speciality Hospital, Hyderabad, India

Sruthi Reddy Thummala

Department of Obstetrician & Gynaecologist, Fellow in Fetal Medicine, Fernandez Hospital, Hyderabad, India

Keywords : Aedes mosquitoes, Dengue fever, Tropical disease

Abstract

Dengue fever is one of the most important mosquito borne neglected tropical disease of major public health concern. The disease may be asymptomatic or may give rise to undifferentiated fever, dengue fever, dengue haemorrhagic fever, or dengue shock syndrome. This review outlines the current knowledge of the dengue virus, mosquito vector, transmission, immune pathogenesis, clinical manifestations, diagnosis, and the treatment and management and prevention and control of these infections and recent advances in vaccine development.